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If B12 levels were low to begin with, longer-term benefits like red blood cell production or nervous system support may take several weeks

As with peripheral arthritis, the utility of vedolizumab for treating axial arthritis in IBD appears limited

Patients should seek medical evaluation for severe pain after injury, inability to bear weight, major swelling, deformity, numbness, weakness, fever, signs of infection, worsening abdominal pain, blood in stool, persistent vomiting, chest pain, shortness of breath, or neurological symptoms

The organisation said: "Additional reviews will be undertaken if new evidence comes to light."

These can help to raise vitamin B12 levels more quickly than an over-the-counter supplement